乙胺嘧啶 | 58-14-0

中文名乙胺嘧啶

中文同义6-乙基-5-(4-氯苯基)-2,4-嘧啶二胺;2,4-二氨基-6-乙基-5-对氯苯基嘧啶;比利美胺;达拉匹林;乙胺嘧啶;息疟定;乙嘧啶,息疟定;马来酰亚胺-羧酸

英文名Pyrimethamine

英文同义2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;Pyrimethamine,5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine;Pyrimethamine (200 mg);PyriMethaMine,darapriM;5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine;BW 50-63;bw50-63

CAS58-14-0

分子式C12H13ClN4

分子量248.71

EINECS200-364-2

结构式

性质

熔点233-234°C

沸点393.35°C (rough estimate)

密度1.2171 (rough estimate)

折射率1.6110 (estimate)

储存条件0-6°C

溶解度Prepare the solution immediately before use. Dissolve 0.25 g in a mixture of 1 volume of methanol R and 3 volumes of methylene chloride R and dilute to 10 mL with the same mixture of solvents. The solution is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method II).

酸度系数(pKa)pKa 7(t=20.0) (Uncertain)

形态neat

水溶解性<0.01 g/100 mL at 21 ºC

最大波长(λmax)276nm(lit.)

Merck14,7985

BRN219864

稳定性Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents.

NIST化学物质信息Pyrimethamine(58-14-0)

(IARC)致癌物分类3 (Vol. 13, Sup 7) 1987

EPA化学物质信息Pyrimethamine (58-14-0)

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。

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