尼美舒利 | 51803-78-2

中文名尼美舒利

中文同义尼美舒利;二盐酸西替利嗪;N-(4-硝基-2-苯氧基)甲基磺酰胺;尼美舒利(标准品);尼美舒利D5;尼美舒利/N-(4-硝基-2-苯氧基)甲基磺酰胺;N-(4-硝基-2-苯氧基苯基)甲磺酰胺;4-硝基-2-苯氧基甲烷磺酰苯胺

英文名Nimesulide

英文同义nimed;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD);4-Nitro-2-phenoxymethanesulfonamide;Nide;Nidol

CAS51803-78-2

分子式C13H12N2O5S

分子量308.31

EINECS257-431-4

结构式

性质

熔点140-146°C

沸点442.0±55.0 °C(Predicted)

密度1.451±0.06 g/cm3(Predicted)

储存条件2-8°C

溶解度Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.

酸度系数(pKa)pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)

形态neat

水溶解性Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.

最大波长(λmax)391nm(H2O)(lit.)

Merck14,6548

稳定性Stable. Incompatible with strong oxidizing agents.

InChIKeyHYWYRSMBCFDLJT-UHFFFAOYSA-N

EPA化学物质信息Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (51803-78-2)

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