异维A酸 | 4759-48-2

中文名异维A酸

中文同义维A酸(维甲酸);13-顺式视黄酸;13-顺维生素A酸;保肤灵;异维甲酸;标准品;异曲替酯;异维A酸原料药

英文名Isotretinoin

英文同义Tretinoin Impurity 1（Tretinoin EP Impurity A）;Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid

CAS4759-48-2

分子式C20H28O2

分子量300.44

EINECS225-296-0

结构式

性质

熔点172-175 °C(lit.)

沸点381.66°C (rough estimate)

密度1.0597 (rough estimate)

折射率1.4800 (estimate)

储存条件−20°C

溶解度Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.

酸度系数(pKa)4.76±0.33(Predicted)

形态Fine Crystalline Powder

颜色Yellow-orange to orange

水溶解性insoluble

最大波长(λmax)354nm(EtOH)(lit.)

Merck14,5228

稳定性Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.

InChIKeySHGAZHPCJJPHSC-YCNIQYBTSA-N

EPA化学物质信息Isotretinoin (4759-48-2)

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