【衡道丨干货】WHO图注英⽂学习手帐 (卵巢黏液性肿瘤篇)

衡道病理特邀撰稿作者翻译了WHO部分图⽚的图注，并用手帐的⽅式进行中英⽂对照，且通过不同颜色的划线将晦涩难懂的英文单词与中⽂翻译同时标注，希望对专业英文的学习有所帮助。上一期分享了 卵巢浆液性肿瘤 ，本期将带来 卵巢黏液性肿瘤 。由于本篇目的以英文学习为主，篇幅有限，故未对各个疾病进行详细阐述。全部图片均来自WHO，若有不恰当之处，还请评论区指正。

WHO图注英文学习手帐  

Mucinous cystadenoma and adenofibroma

黏液性囊腺瘤和黏液性腺纤维瘤

Definition

Mucinous cystadenoma and adenofibroma are benign tumours with gastrointestinal or Müllerian-type mucinous epithelium.

定义

黏液性囊腺瘤和黏液性腺纤维瘤是一种卵巢良性肿瘤，衬覆胃肠型或苗勒型上皮。

Essential and desirable diagnostic criteria

Essential: tumour withcysts and glands lined by benign mucinous epithelium with no architectural complexity or cytological atypia.

必要和可取的诊断标准

必需:肿瘤的囊腔和腺体衬覆良性黏液上皮不伴有结构复杂性或细胞异型性。

Fig. 1.27 Mucinous cystadenoma.

A The cyst is lined by tall columnar cells with abundant mucinous cytoplasm and bland basally situated nuclei.

B Stromalluteinization. Stromal cells adjacent to the mucinous epithelium show abundant granular eosinophilic or pale cytoplasm and round nuclei.

图1.27黏液性囊腺瘤。

A囊肿内衬覆高柱状细胞，胞浆黏液丰富，核位于基底。

B间质黄素化。紧邻黏液上皮的间质细胞，胞浆丰富、颗粒状、嗜酸性或淡染，胞核呈圆形。

Fig.1.28 Mucinous cystadenoma with mucin granuloma. The mucinous glands are ruptured, with tumour epithelium displaced into stroma and surrounded by extracellular mucin and histiocytes, including multinucleated giant cells. This finding should not be misinterpreted as stromal invasion.

图1.28黏液性囊腺瘤伴黏液肉芽肿。黏液腺体破裂，肿瘤上皮移位至间质，被细胞外黏液和组织细胞(包括多核巨细胞)包围。这一发现不要误诊为间质浸润。 

Mucinous borderline tumour

卵巢交界性黏液性肿瘤

Definition

Mucinous borderline tumour (MBT) is an architecturally complex non-invasive mucinous neoplasm with gastrointestinal-type differentiation.

定义

卵巢交界性黏液性肿瘤(MBT)是一种具有胃肠型上皮分化、结构复杂的非浸润性黏液性肿瘤。

Essential and desirable diagnostic criteria

Essential: tumour with gastrointestinal-type mucinous epithelium lining cysts with variable degrees of epithelial stratification,tufting, and villous or slender filiform papillae, in at least 10% of the tumour; low-grade nuclear atypia (except if intraepithelial carcinoma); absence of stromal invasion (except if microinvasion or microinvasive carcinoma).

必要和可取的诊断标准

必要条件:肿瘤囊壁衬覆胃肠型黏液上皮，并且至少10％的上皮呈复层、簇状、绒毛状或细长丝状乳头结构；低级别核异型性(上皮内癌除外)；无间质浸润(微浸润或微浸润性癌除外)。

Fig. 1.29 Mucinous borderline tumour.

A The cyst lining shows architectural complexity, with somevillous architecture and epithelial stratification.

B Mucinous borderline tumour lined by stratified epithelium with mild to moderate atypia.Mitotic figures are present.

图1.29交界性黏液性肿瘤。

A囊壁衬覆上皮结构复杂，伴有绒毛状结构和复层上皮。

B交界性黏液性肿瘤，衬覆复层上皮，细胞轻至中度异型。核分裂象可见。

 Fig. 1.30 Mucinous borderline tumour with intraepithelial carcinoma. The epithelium has a reduced amount of mucin, an increased N:C ratio, and enlarged nuclei with severe atypia characterized by vesicular chromatin and prominent nucleoli.

图1.30交界性黏液性肿瘤伴上皮内癌。上皮黏液蛋白减少，N:C比值增加，核增大，重度非典型性，以泡状染色质和显著的核仁为特征。

Fig. 1.31 Mucinous borderline tumour with microinvasive carcinoma.

At the base of the mucinous borderline tumour, a small focus within stroma contains markedly crowded andhaphazardly oriented nests. The qualitative features are akin to frankly invasive mucinous carcinoma (infiltrating pattern). Inset: The clusters of tumour cells in the focus of microinvasive carcinoma show marked cytological atypia.

图1.31交界性黏液性肿瘤伴微浸润性癌。

在交界性黏液性肿瘤的底部，基质内的病灶显示有明显拥挤和无序的巢。特征类似于浸润性黏液癌(浸润型)。插图:微浸润癌灶内的肿瘤细胞簇显示明显的细胞非典型性。

Flg. 1.32 Mucinous borderline tumour with microinvasion.

A The clusters of tumour cells in the area of microinvasion measure < 5 mm in linear dimension.

B The clusters of tumour cells in the area of microinvasion show mild cytological atypia.

图1.32交界性黏液性肿瘤伴微浸润。

A微浸润区肿瘤细胞簇的线性距离小于5毫米。

B微浸润区中肿瘤细胞簇显示轻微的细胞非典型性。

A Peritoneal fluid cyology shows epthelial aggregates with nuclear stratification, moderate epithelial atypia, and conspicuous nucleoli.

B Peritoneal fluid cytology shows epithelial clusters with nuclear atypia and focal glandular configuration.

图1.33交界性黏液性肿瘤破裂。

A腹水细胞学显示上皮细胞聚集伴有核复层，上皮细胞呈中度非典型性并有显著的核仁。

B腹水细胞学显示上皮细胞簇伴核非典型性和局灶腺样结构。

Mucinous carcinoma of the ovary

卵巢黏液性癌

Definition

Mucinous carcinoma is an invasive mucinous neoplasm composed ofgastrointestinal-type cells.

定义

黏液性癌是一种由胃肠型细胞组成的浸润性黏液性肿瘤。

Essential and desirable diagnostic criteria

Essential: mucinous tumour with cytological atypia andexpansile/confluent and/or infiltrative/destructive invasion, measuring at least 5 mm in linear extent.

必要和可取的诊断标准

必需：黏液性肿瘤，细胞异型性，可呈膨胀/融合和/或浸润/破坏性侵袭，线性范围至少5mm。

Fig. 1.34 Mucinous carcinoma.

The tumour exhibits infiltrative/destructive growth, with irregularly shaped glandsarranged haphazardly within altered stroma.

图1.34黏液性癌。

肿瘤呈浸润性/破坏性生长，不规则的腺体随意排列在间质中。

Fig. 1.35 Mucinous carcinoma.

The tumour exhibits expansile/confluent growth, with anastomosing/labyrinthine architecture and minimal to absent stroma.

图1.35黏液性癌。

肿瘤呈膨胀/融合生长，伴有吻合/迷路状结构，间质极少或缺乏。

整理：南瓜子儿

审核：樊月

设计：鹏飞

编辑：V

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