硬膜外麻醉复合全身麻醉与单纯全身麻醉在新生儿胃肠道手术中的效果比较:一项随机对照试验

2021
11/01

+
分享
评论
米勒之声
A-
A+

硬膜外麻醉复合全身麻醉与单纯全身麻醉在新生儿胃肠道手术中的效果比较

本文由“罂粟花”授权转载

硬膜外麻醉复合全身麻醉与单纯全身麻醉在新生儿胃肠手术中的效果比较:一项随机对照试验 

63121635462379831

贵州医科大学 麻醉与心脏电生理课题组

翻译:马艳燕   编辑:潘志军   审校:曹莹

背  景

术后肠梗阻是在全身麻醉下行胃肠道手术的常见并发症。本研究的目的是研究在行择期胃肠道手术的新生儿中,胃肠道功能的快速恢复是否与硬膜外麻醉联合全身麻醉有关。

方  法

一项随机对照试验,包括60名在大学附属医院行胃肠道手术的新生儿。30例新生儿接受硬膜外麻醉复合全身麻醉(CEGA),另外30例新生儿单独行全身麻醉(GA)。主要结局指标是术后接受全肠内营养的时间。次要结局指标是术后通便时间、鼻胃管引流时间和感染时间。

结  果

排除了2名在硬膜外置管时反复尝试均未成功的CEGA组的新生儿后,共有58名新生儿完成了研究(CEGA:28;GA:30)。CEGA组比GA组更早耐受全肠内营养(4.0天 vs 8.0天;P=0.0001)。CEGA组的通便时间较短(3.5天 vs 5.0天;P =0.0001)。两组间鼻胃管引流时间相似(7.0天vs7.0天;P =0.9502)。CEGA组术后感染的新生儿较少(35.7% vs 60.0%;P=0.038)。

38791635462379914

73171635462379999

26681635462380076

72281635462380168

95841635462380367

58241635462380586

   

结  论

硬膜外麻醉联合全身麻醉可促进新生儿胃肠道手术后胃肠道功能恢复和降低感染风险。

原始文献

Version:0.9 StartHTML:0000000105 EndHTML:0000031936 StartFragment:0000000141 EndFragment:0000031900

Gannam-Somri L, Matter I, Hadjittofi C. Combined epidural-general anaesthesia vs general anaesthesia in neonatal gastrointestinal surgery: A randomized controlled trial. Acta Anaesthesiol Scand. 2020 Jan;64(1):34-40.



Combined epidural‐general anaesthesia vs general anaesthesia in neonatal gastrointestinal surgery: A randomized controlled trial

Abstractive

Background: Post‐operative ileus is a frequent complication of gastrointestinal surgery under general anaesthesia. The aim of this study was to investigate whether combined epidural‐general anaesthesia is associated with expedited gastrointestinal function recovery in neonates undergoing elective gastrointestinal surgery.

Methods: randomized controlled trial including 60 neonates who underwent gastrointestinal surgery at a university hospital was performed. Thirty neonates received combined epidural‐general anaesthesia (CEGA), and 30 neonates received general anaesthesia (GA) alone. The primary outcome was the post‐operative time to toler‐ance of full enteral nutrition. The secondary outcomes were the post‐operative time defaecation, the duration of nasogastric drainage, and infections.

Results: After excluding two neonates from the CEGA group, where repeated attempts at epidural catheterization were unsuccessful, a total of 58 patients completed the study (CEGA: 28; GA: 30). Full enteral nutrition was tolerated earlier in CEGA vs the GA group (4.0 vs 8.0 days; P=0.0001). Time to defaecation was shorter in the CEGA group (3.5 vs 5.0 days; P=0.0001). Duration of nasogastric drainage was similar between groups (7.0 vs 7.0 days; P=0.9502). Fewer patients in the CEGA group experienced post‐operative infection (35.7% vs 60.0%; P=0.038).

Conclusion: Combined epidural‐general anaesthesia is associated with expedited gastrointestinal function recovery and a lower infection risk after gastrointestinal surgery in neonates.

本文由“健康号”用户上传、授权发布,以上内容(含文字、图片、视频)不代表健康界立场。“健康号”系信息发布平台,仅提供信息存储服务,如有转载、侵权等任何问题,请联系健康界(jkh@hmkx.cn)处理。
关键词:
全身,麻醉,新生儿,时间,胃肠道

人点赞

收藏

人收藏

打赏

打赏

我有话说

0条评论

0/500

评论字数超出限制

表情
评论

为你推荐

推荐课程


社群

精彩视频

您的申请提交成功

确定 取消
剩余5
×

打赏金额

认可我就打赏我~

1元 5元 10元 20元 50元 其它

打赏

打赏作者

认可我就打赏我~

×

扫描二维码

立即打赏给Ta吧!

温馨提示:仅支持微信支付!