SCI晨读:同伴支持干预对中风幸存者生理和社会心理结局的影响:系统评价和Meta分析
同伴支持干预对中风幸存者生理和社会心理结局的影响:
系统评价和Meta分析
分享智慧
共同成长
摘要
背景
中风幸存者在出院后仍有大量未满足的需求。同伴支持干预可能在卒中管理中发挥重要作用,但证据尚不清楚。
目标
确定同伴支持干预对中风幸存者生理和社会心理结果的影响;并确定中风幸存者同伴支持干预的关键特征。
设计
系统评价和荟萃分析。
综述方法
检索了7个英文数据库和4个中文数据库,以确定符合条件的文章。两名评价员对符合条件的研究进行筛选,评估偏倚风险,并独立提取数据。使用Cochrane 偏倚风险工具的第 2 版评估随机对照试验的偏倚风险,使用非随机干预研究中的偏倚风险工具评价准实验研究。使用推荐分级评估、制定和评价分析器指南制定工具评估证据质量。使用 Review Manager 5.3 进行Meta分析,当Meta分析不合适时进行描述性分析。
结果
纳入了 11 项研究。同伴支持干预可以改善日常生活活动(MD = 15.53,95% CI:1.39 至 29.68;P =0.03,I 2 = 99%;证据质量极低)、肢体功能、抑郁(SMD = -1.27, 95% CI:-2.18 至 -0.36;P = 0.006,I 2 = 91%;证据质量极低)和焦虑。尽管汇总分析显示社会参与(SMD= 0.74,95% CI:0.09 至 1.39;P=0.03,I 2 = 69%;证据质量低)和生活质量(SMD = 0.41,95% CI:0.09 至0.73;P = 0.01,I 2 = 0%; 低质量证据)在同伴支持干预后有所改善,由于数据不足而未合并的研究得出了不一致的结果。
结论
中风幸存者可以从同伴支持干预中受益,以改善他们的身心结局。关于同伴支持干预对社会参与和生活质量的影响的证据非常不确定。应该指出的是,证据的质量从非常低到低不等,因此强调需要更多更高质量的研究来证实这些发现。
Abstract
Background
High level of unmet needs were reported by stroke survivors after hospital discharge. Peer support interventions may play a valuable role in the management of stroke, but the evidence is unclear.
Objectives
To determine the effects of peer support interventions on physical and psychosocial outcomes of stroke survivors; and to identify the key characteristics of peer support interventions for stroke survivors.
Design
A systematic review and meta-analysis.
Review methods
Seven English databases and four Chinese databases were searched to identify eligible articles. Two reviewers screened the eligible studies, appraised the risk of bias, and extracted the data independently. Version 2 of the Cochrane risk-of-bias tool was used to evaluate the risk of bias for randomized controlled trials, while the Risk of Bias in Non-randomized Studies of Interventions tool was used for the quasi-experimental studies. The Grading of Recommendations Assessment, Development and Evaluation profiler Guideline Development Tool was used to assess the quality of evidence. Meta-analyses were conducted using Review Manager 5.3, and narrative analyses were performed when meta-analysis was inappropriate.
Results
Eleven studies were included. Peer support interventions could improve the activities of daily living (MD = 15.53, 95% CI: 1.39 to 29.68; P=0.03, I2 = 99%; very low quality of evidence), limb function, depression (SMD = -1.27, 95% CI: -2.18 to -0.36; P = 0.006, I2 = 91%; very low quality of evidence) and anxiety. Although pooled analysis showed that social participation (SMD= 0.74, 95% CI: 0.09 to 1.39; P=0.03, I2 = 69%; low quality of evidence) and quality of life (SMD = 0.41, 95% CI: 0.09 to 0.73; P = 0.01, I2 = 0%; low quality of evidence) improved after peer support interventions, the studies which were not pooled due to insufficient data drew inconsistent results.
Conclusions
Stroke survivors may benefit from peer support interventions to improve their physical and psychological outcomes. The evidence about the impact of peer support interventions on social participation and quality of life is very uncertain. It should be noted that the quality of evidence ranged from very low to low, thus highlighting the need for more research of higher quality to substantiate these findings.
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